INTRODUCTION: Traumatic spinal cord injury (tSCI) is frequently observed in polytrauma patients.

CONCLUSION: Older adults with lower SES experienced polypharmacy or co-prescribing suggesting a prescribing cascade more frequently than those with higher SES. Within the lower SES groups, females more frequently than males had evidence of co-prescribing suggesting a prescribing cascade. Considering the role of sex and gender-related sociocultural factors may help to better understand some contributors to polypharmacy and prescribing cascades. The research applications are highlighted in our...

CONCLUSIONS: The rate of publications on rTKA has increased substantially in media sources and peer-reviewed journals, with the volume of media articles far outpacing RCTs on the topic. More precise component positioning was the most consistently reported benefit of rTKA in RCTs. However, media sources also reported a range of other, less well-supported benefits, and employed overwhelmingly positive tones regarding rTKA, more so than is supported by mixed clinical results. Efforts to ensure that...

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CONCLUSION: Based on the Enneking classification, our experience has shown that a reasonable surgical approach for primary active and invasive metatarsal ABC is en bloc resection and reconstruction with fibula allograft. This method has a low risk of recurrence and does not result in significant functional impairment.

CONCLUSIONS: Both 6SHG and 8SHG produced graft diameters <8 mm. Data regarding PROMs suggested good patient satisfaction based on established criteria. Re-rupture and return-to-sport rates were 4.8% and 75.9%, respectively.

BACKGROUND: Randomized-clinical trials (RCTs) are the gold-standard for comparing health care interventions, but can be limited by early termination, feasibility issues, and prolonged time to trial reporting. Adaptive clinical trials (ACTs), which are defined by pre-planned modifications and analyses that occur after starting patient recruitment, are gaining popularity as they can streamline trial design and time to reporting. As adaptive methodologies continue to be adopted by researchers, it...